Trials have shown an increase in all-cause mortality associated with supplementation with vitamin A, vitamin E, and β-carotene.
No benefits or reductions in all-cause mortality were shown for vitamin C or selenium.
Further Reading / References
Antioxidant supplements to prevent mortality. JAMA 2013;310(11):1178-1179.
Ann Intern Med. 2005;142:37–46. Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality.