“This presentation is consistent with β-thalassemia minor trait in a generally asymptomatic patient. Hemoglobin electrophoresis will be abnormal, with HbA2 increased and HbA decreased. The free T4 level is likely to be normal in a patient with a normal TSH level. A ferritin level is also likely to be normal given the normal levels of hemoglobin and hematocrit. A fluorescent spot test is used to screen for G-6-PD deficiency, which would be associated with bite cells and Heinz bodies. A vitamin B12 level would be useful for evaluating macrocytosis, which is not present in this patient.” ABFM Critique
Iron deficiency and other types of anemia in infants and children. Am Fam Physician 2016;93(4):270-278.
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