- History of colonization or infection with MRSA
- Recent (within 3 months) hospitalization or concurrent prolonged hospitalization > 2 weeks
- Prolonged hospital stay
- Residence in a long-term care facility (e.g. transfer from a nursing home or subacute facility)
- Recent antibiotic therapy
- HIV infection
- Men who have sex with men
- Injection drug use
- Hemodialysis
- Incarceration
- Military service
- Sharing needles, razors, or other sharp objects
- Sharing sports equipment
- Diabetes
- Swine farming