Proton Pump Inhibitors cause osteoporosis and low magnesium

Association of Long-term Proton Pump Inhibitor Therapy with Bone Fractures and effects on Absorption of Calcium, Vitamin B12, Iron, and Magnesium

http://www.fda.gov/Drugs/DrugSafety/ucm245011.htm

http://www.ncbi.nlm.nih.gov/pubmed/22890365