Light’s criteria (= Exudate Criteria) are 99.5% sensitive for diagnosing exudative effusions and differentiate exudate from transudative effusions in 93-96% of cases.
Light’s criteria for fluid being exudate are:
- Pleural fluid protein to serum protein ratio > 0.5,
- Pleural fluid LDH to serum LDH ratio > 0.6, and/or
- pleural LDH > 2/3rds (i.e. 0.67 times) the upper limit of normal for serum LDH)
NB: 0.67 = 2/3
Mnemonic. Exude Light. Light’s criteria define an exudative solution. If the criteria are not fulfilled, then the solution is a transudate.