Immunosuppression is defined as:
- Treatment with glucocorticoids (treatment with the equivalent of 20 mg/day of prednisone for 2 weeks or more, and discontinuation within the previous 3 months)
- Ongoing treatment with effective doses of 6-MP/azathioprine or discontinuation within the previous 3 months
- Treatment with methotrexate or discontinuation within the previous 3 months
- Treatment with infliximab or discontinuation within the previous 3 months
- Significant protein-calorie malnutrition
Ref: Wasan SK, Baker SE, Skolnik PR, Farraye FA: A practical guide to vaccinating the inflammatory bowel disease patient. Am J Gastroenterol 2010;105(6):1231–1238.