Immunosuppression is defined as:

  • Treatment with glucocorticoids (treatment with the equivalent of 20 mg/day of prednisone for 2 weeks or more, and discontinuation within the previous 3 months)
  • Ongoing treatment with effective doses of 6-MP/azathioprine or discontinuation within the previous 3 months
  • Treatment with methotrexate or discontinuation within the previous 3 months
  • Treatment with infliximab or discontinuation within the previous 3 months
  • Significant protein-calorie malnutrition

Ref:     Wasan SK, Baker SE, Skolnik PR, Farraye FA: A practical guide to vaccinating the inflammatory bowel disease patient. Am J Gastroenterol 2010;105(6):1231–1238.

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