• Irritant Contact Dermatitis.
  • Allergic Contact Dermatitis
  • Diaper Candidiasis
  • Impetigo; Streptococcal infection.
  • Cellulitis
  • Seborrheic Dermatitis and Psoriasis
  • Infected Contact Dermatitis (contact dermatitis with superinfection / suprainfection) e.g.  Staphylococcal pustulosis. Diaper candidiasis is often a superinfection.
  • Herpes simplex virus (HSV)  infection
  • Molluscum
  • Warts
  • Scapies

Selected Differential Diagnosis Comparison for Diaper Rash

Am Fam Physician. 2014 Jun 15;89(12):973-974.

CONDITION SKIN SYMPTOMS
COLOR ULCERATION/EROSION PUSTULES OTHER

Candidiasis

Erythematous (beefy-red)

No

Yes

Satellite lesions

Cellulitis

Erythematous

No

Yes

Edema that may feel fluctuant

Herpes simplex virus infection

Erythematous base

Yes

No

Vesicles

Impetigo

Honey-colored and erythematous

Superficial

Yes

Crusting

Irritant contact dermatitis

Erythematous

Yes

No

Shiny, smooth skin

 

“Irritant contact dermatitis is the most common skin eruption seen in the diaper area and is caused by skin rubbing against a wet, soiled diaper or another part of the skin. This process can lead to chafing, or well-defined red scaly patches that appear on the anterior thighs, scrotum, vulvae, suprapubic area, or buttocks with sparing of the skin creases.”
Commonly seen when child is having diarrea.

Reference and Resources

Clinical Pediatrics. Vol 56, Issue 5_suppl, pp. 16S – 22S. April 18, 2017.  Differential Diagnosis of Diaper Dermatitis

Am Fam Physician. 2014 Jun 15;89(12):973-974.

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