Pharmacy and Therapeutics
How does Colchicine work to treat acute gout? In gout, colchicine concentrates in neutrophils (PMNs) and inhibits microtubule formation. This prevents neutrophils from migrating to inflamed joints and exerting their activity there. Neutrophils that migrate to the...
Pharmacy and Therapeutics
Labetalol = 1st line. Labetalol 100-400 mg BID. Start 100 mg PO BID. May increase by 100 mg BID q2-3 days. Max dose: 2400 mg /day. Methyldopa 250 -500 mg PO BID. Start 250 mg PO BID, then adjust q2 days. Max 3000 mg /day. Nifedipine extended-release 30 to 90 mg daily....
Pharmacy and Therapeutics
“Glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonists and dipeptidyl peptidase-4 inhibitors (DPP-4i), exert their actions through potentiation of incretin receptor signaling. Incretins are gut-derived hormones, principally GLP-1 and glucose-dependent...
Clinic A/P, adults, Clinic A/P, Peds, Hospital A/P, Adults, Hospital A/P, Peds, Pharmacy and Therapeutics
Severe Symptomatic Hypertension (Hypertensive Crisis) IV Drugs Oral Medications Clonidine 0.1-0.2 mg Labetalol 200-400mg BID. Start: 100mg po BID, may increase by 200 mg / dayq2-3 days. Max 2400 mg/day. May divide dose TID. Taper dose over 1-2 wks to D/C. Hydralazine...
Pharmacy and Therapeutics
https://www.motrin.com/children-infants/dosing-charts
Pharmacy and Therapeutics
Acetaminophen (Tylenol) Dosing Chart by Weight for infants and children Child’s weight (pounds) 6-11 12-17 18-23 24-35 36-47 48-59 60-71 72-95 96+ lbs Liquid 160 mg/ 5 milliliters (mL) 1.25 2.5 3.75 5 7.5 10 12.5 15 20 mL Liquid 160 mg/ 1 teaspoon (tsp) —...