Clinic A/P, adults, Clinic A/P, Peds, Hospital A/P, Peds, Pharmacy and Therapeutics
Treatment of Acute Urticaria (Hives) -R/o anaphylaxis. Epinephrine IM is urgently indicated for laryngeal swelling and respiratory symptoms. This should be done first, before anything else. -H1-antihistamines (1st-line tx). 2nd Generation H1 antihistamines are...
Pharmacy and Therapeutics
CAP in children is treated based on age. The most likely etiologic agents in a school-age child are Mycoplasma pneumoniae, Chlamydia pneumoniae, and Streptococcus pneumoniae. Age Antibiotic Most common Causative Agent *2 months to 5 years High-dose oral amoxicillin...
Pharmacy and Therapeutics
Fluoroquinolones, Vancomycin, Telavancin, and Bactrim MOA Side Effects Common uses Comments Fluoroquinolones -1st Gen: Nalidixic acid -2nd Gen: Ciprofloxacin, levofloxacin, etc. -3rd Gen: Gatifloxacin -4th Gen: Moxifloxacin and Gemifloxacin Inhibits the enzyme DNA...
Pharmacy and Therapeutics
Tylenol, Ibuprofen, Naproxen, Aspirin – Pediatric doses Acetaminophen 10-15mg/kg/dose po q4-6h; Max daily dose = 4000 mg (i.e. 4 grams) NSAIDS: Ibuprofen 5-10mg/kg/dose po q4-6h Naproxen 5-10mg/kg/dose po q12h (i.e. 10-20mg/kg/DAY po divided q12h): Max: 1000...
Pharmacy and Therapeutics
Our ribosomes are different from bacterial ribosomes. We have a larger 80S particle and bacteria have a smaller 70S particle. We use this difference to create drugs that selectively target bacterial ribosomes. The 70S bacterial ribosome has two subunits, the 50S and...
Pharmacy and Therapeutics
All penicillin family antibiotics have the beta-lactam ring and are therefore also called beta-lactam antibiotics. The penicillins are bactericidal. Beta-Lactam Antibiotics MOA: Inhibits bacterial cell wall synthesis by competitive inhibiting the transpeptidase...
