Pharmacodynamics versus pharmacokinetics

Pharmacokinetics: Kinetics  = Has to do with movement. How the body moves and metabolizes the drug and eventually excretes it.  Dictionary.com says Pharmacokinetics is “the study of the movement of drugs in the body, including the processes of absorption,...

Bacteriostatic versus Bactericidal

Bacteriostatic versus Bactericidal Mechanisms of Action in the Treatment of Gram-Positive Bacterial Infections Definitions: “”Bacteriostatic” means that the agent prevents the growth of bacteria (i.e., it keeps them in the stationary phase of...

Clindamycin

How does clindamycin inhibit toxin production by Group A Strep and Staphylococcus aureus (both MSSA and MRSA)?  Answer: The toxins are proteins. Translation of mRNA to make proteins happens on the ribosomes. Clindamycin blocks the ribosomes (it’s an...

2nd Generation H1-antihistamines

2nd-generation H1 antihistamines are only available in oral formulations and include the following: Cetirizine (Zyrtec) 10mg PO QD for adults and children 6 years and older. May be increased to BID in adults if needed. use 5mg PO QD for children aged 2-5 year sold....

Opioid Allergies and Cross-reactivity

A patient has a history of anaphylaxis to morphine, almost died from it. Are there some opioids you can give to them? Yes. You simply need to choose one that is structurally different. Opioids are classified into three groups: Group 1 – The Natural occurring...