Pharmacy and Therapeutics
In 2016, the ADA published an excellent algorithm that I use for treating my diabetes patients. Source: Diabetes Care 2016 Jan; 39(Supplement 1): S52-S59 Larger image. Reference Diabetes Care 2016 Jan; 39(Supplement...
Pharmacy and Therapeutics
Long-term PPI use increases the risk of: Clostridium difficile-associated diarrhea. Other enteric infections Osteoporosis and Osteoporosis fractures. Fractures (of the Hip, wrist, and spine) Community-acquired pneumonia Hypomagnesemia Cardiac events when...
Pharmacy and Therapeutics
Thiazolidinediones (TZDs) improve hyperglycemia by improving insulin resistance and by maintaining or improving beta-cell secretory function. Side effects “One of the side effects of TZDs is that they can cause fluid retention, especially in patients with...
Pharmacy and Therapeutics
Heart Failure with Reduced Left Ventricular Ejection Fraction (i.e. <40%) “Systolic heart failure, or heart failure with a reduced left ventricular ejection fraction (<40%), should be managed with an ACE inhibitor and a $-blocker. If there is volume...
Pharmacy and Therapeutics
Diabetes = a problem of high blood sugars (glucose). The solution is anything that will lower blood sugars. *Five mechanisms, one goal. The goal is to lower blood sugars! The first three reduce the amount of sugars entering the blood streams. The last two take sugar...
Pharmacy and Therapeutics
The 3 most effective oral agents for lowering hemoglobin A1c in diabetic patients are Metformin, Sulfonylureas, and Thiazolidinediones. MEDICATION, TYPICAL DOSE & ROUTE 1. Biguanides (Metformin) – Decrease A1C ~ 1.5% Metformin 500 to 1,000 mg PO twice daily...