Antidotes

Toxicity  Example situation Antidote Magnesium toxicity, e.g. in a woman who has preeclampsia who is being treated with magnesium who becomes apnea and areflexia. Calcium e.g. Calcium gluconate (can be given via peripheral IV). Calcium chloride needs a central line....

Sevelamer

Sevelamer is taken by patients with CKD and hypercalcemia to lower their calcium. How does it work? By blocking intestinal absorption of phosphate, which lowers PTH secretion. Sevelamer is a phosphate binder. Calcium acetate is also a phosphate binder. Secondary...

ACE inhibitors

Increase in creatinine upon initiating ACE inhibitors You start a lisinopril in a patient and it worked well for the patient and brings her BP to your goal. However, her creatinine rises from 1.25 to 1.5. What should you do? Continue the current medication. “ACE...