Cold Intolerance (Feeling Cold), Differential Diagnosis

Idiopathic Advanced age, thin woman Psychiatric: Anxiety, Depression Hypothyroidism Anemia Raynaud’s phenomenon; Scleroderma Weight loss, malnutrition Chronic severe illness; General poor health Hypoglycemia Anorexia Nervosa Hypopituitarism Lupus Hypothalamus...

Leg Pain, Differential Diagnosis

Musculoskeletal Arthritis Fracture Gout Muscle cramps Lumbar disc disease Vascular Varicose veins Deep vein thrombosis Arterial occlusion Intermittent Claudication Infection Cellulitis Tendinitis Osteomyelitis Septic arthritis Neuropathic Medial tibial stress syndrome...

Insomnia (Sleep Disturbances), Differential Diagnosis

Primary insomnia (psychophysiological) Depression Anxiety Post-traumatic stress Substance abuse/use, e.g. caffeine, nicotine, cocaine, steroids, alcohol, others) Poor sleep hygiene Obstructive sleep apnea Gastroesophageal reflux Medication-related insomnia (see below)...

Hypotension and Shock, Differential Diagnosis

Hypovolemia Hemorrhage (trauma, GI bleeding) Vomiting, diarrhea Drugs: e.g. antihypertensives Vessels Cardiomyopathy Hypertrophic cardiomyopathy Myocardial infarction Cardiac tamponade Atrial myxoma Anaphylaxis Pulmonary embolus Ruptured aneurysm Aortic stenosis...

Pruritus (Itchy Skin) Differential Diagnosis

Dermatologic causes of pruritus Dry skin (Xerosis) Atopic dermatitis (eczema) Allergic/irritant contact dermatitis Urticaria (hives) Dermatophyte (tinea) infections – e.g. Pedis, Corposis, Cruris, Capitis. Scabies Pediculosis (lice infestation) Insect Bites...

Hematuria, Differential Diagnosis

Distinguish between Microscopic hematuria vs. Gross Hematuria. Transient unexplained hematuria Urinary tract infection Urethritis Benign prostatic hyperplasia Stones / Urinary calculi Menstruation (contaminated urine) Exercise Trauma Atrophic vaginitis Bladder cancer...