Celiac Disease

Diagnosis Anti-TTG IgA (i.e. Anti-Tissue Transglutaminase IgA) is the first test you do. It is 1st-line. It has a sensitivity of 95% and specificity of 95%. You may add a total IgA because patients with IgA deficiency are at risk of a false negative. In IgA deficient...

Lactose Intolerance

Diagnosis Common symptoms: Bloating, flatulence, and abd. pain. Children may have diarrhea as well and adolescents may have nausea/vomiting. Cause: Caused by lactose malabsorption. Patients have low levels of lactase in the duodenum and so cannot digest the...

Vitamin B1 (Thiamine)

Thiamine (vitamin B1) deficiency is most commonly seen in chronic alcoholics. It usually presents with beriberi (neurological and cardiovascular disease), Wernicke-Korsakoff syndrome (neuro-psychiatric disorder), and optic neuropathy (bilateral visual loss or impaired...

Epistaxis, Posterior

  Here is a real scenario that happened to a hospitalist. Pt with posterior epistaxis is bleeding severely. Coughing. O2 sats start going down. Is tachycardia and tachypnea. Patient has cirrhosis and INR is elevated. You call ENT, and ENT says he is in a surgery...