Constipation, Opiate Induced

Lubiprostone is an effective medication approved for the treatment of opiate induced constipation. Opiates bind delta, kappa and mu receptors. Although all three receptors are related to pain mitigation, these are all also linked to decreased gastrointestinal...

Toxic Megacolon

Toxic megacolon is a complication of infectious colitis or inflammatory bowel disease and is potentially lethal. DX: Diagnosis is made with evidence on plain radiography of colonic dilatation along with clinical signs such as fever, leukocytosis, anemia, tachycardia,...